Our services

Full-spectrum integrative medicine, from prolotherapy to Perispinal Etanercept.

Six programs, one clinic. Every service below is delivered by Dr. Cruz personally, guided by ultrasound or fluoroscopy where precision matters, and rooted in thirty years of emergency, anesthesia, and pain procedure training.

The programs

Six programs, under one roof.

Each service is tied to a primary set of conditions. If you are unsure where you fit, start with a consultation, we will point you to the right program on the first call.

Perispinal Etanercept & Neuro Brain Protocol at Kentuckiana Integrative MedicineFlagship

Neurological recovery

Perispinal Etanercept & Neuro Brain Protocol

For stroke, TBI, Parkinson's, even years after the event.

Dr. Cruz was trained directly by Dr. Edward Tobinick, MD, the physician who pioneered Perispinal Etanercept. Published research on 600+ patients shows roughly 80% neurological improvement, with measurable recovery decades after the original injury.

Explore neurological
The Kentuckiana Ketamine Institute at Kentuckiana Integrative MedicineFlagship

Mental health

The Kentuckiana Ketamine Institute

10+ years of IV ketamine. 5R Protocol. Zero serious adverse events.

For treatment-resistant depression, PTSD, OCD, bipolar, and chronic pain. Our proprietary 5R Protocol layers IV ketamine with amino acids, NAD+, magnesium, and targeted nutrition, reported response rates of 80–90% vs. 65–75% for standard ketamine and 36% for single antidepressants.

Explore ketamine
Prolotherapy, PRP & Messenger Signaling Cell at Kentuckiana Integrative MedicineFlagship

Regenerative medicine

Prolotherapy, PRP & Messenger Signaling Cell

Rebuild tissue. Skip surgery. Stay active.

One of the earliest U.S. clinics providing cellular biologics (since 2010). Prolotherapy, Prolozone, Triple PRP, and personal stem cell therapy using the patient's own Bone Marrow Aspirate, all delivered with ultrasound and fluoroscopic guidance.

Explore regenerative
IV Chelation & Plaquex at Kentuckiana Integrative Medicine

Cardiovascular

IV Chelation & Plaquex

Heart disease, peripheral artery disease, and vascular support, rooted in the TACT trial.

Certified in IV Chelation. Our cardiovascular protocols are informed by the peer-reviewed TACT trial led by Harvard cardiologist Dr. Gervasio Lamas, MD. We treat patients with advanced heart disease, PAD, and brain vascular disease.

Explore cardiovascular
HCG Lifestyle & Semaglutide Programs at Kentuckiana Integrative Medicine

Medical weight loss

HCG Lifestyle & Semaglutide Programs

Supervised weight loss, full lab panel, and a plan you can keep.

A physician-supervised program built around Dr. Cruz's proprietary HCG Lifestyle Plan, with Phentermine, Semaglutide, Lipotropic injections, and coaching. Men's and women's tracks. Roughly 90% of our patients reach their target weight and keep it off.

Explore weight loss
Wound Care Medical Center at Kentuckiana Integrative Medicine

Advanced wound care

Wound Care Medical Center

Heal non-healing wounds in months, not years.

FDA-approved regenerative products under 21 CFR 1271.10 for chronic and acute wounds. Medicare-covered. For the patient who has been in dressing changes for years without progress.

Explore wound care

Begin

We treat what others have given up on.

Call for a consultation. Tell us what you've tried, what hasn't worked, and what a better year looks like. We'll tell you, plainly, whether we can help.

405 E. Court Ave., Ste 102, Jeffersonville, IN 47130 · Mon–Fri · 9 AM – 5 PM